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Mycobacterium ulcerans Infection in French Guiana: Current State of Knowledge

Auteur(s) : Pierre Couppié, Romain Blaizot, Camilla J. Velvin, Maylis Douine, Marine Combe, Mathieu Nacher, Rodolphe E. Gozlan, Gerd Pluschke, Katharina Röltgen

Authors

Pierre Couppié,corresponding author1,2 Romain Blaizot,1,2 Camilla J. Velvin,3 Maylis Douine,2,4 Marine Combe,3 Mathieu Nacher,2,4 and Rodolphe E. Gozlan3.

 

Affiliations

1 Service de dermatologie, Cayenne Hospital, Cayenne Cedex, French Guiana

2 Université de Guyane, EA3593 Ecosystèmes Amazoniens et Pathologie Tropicale, Cayenne, French Guiana

3 UMR ISEM, Université de Montpellier, CNRS, IRD, EPHE, Montpellier, France
4 Centre d’Investigation Clinique, CIC Inserm 1424, Cayenne Hospital, Cayenne Cedex, French Guiana

 

Abstract

M. ulcerans infections (Buruli ulcer; BU) have been reported in French Guiana since the 1960s [1]. It is striking to see that French Guiana concentrates most of the cases of BU in America with only a few cases reported in Suriname, Peru, Mexico and Bolivia in the past [2, 3]. Either BU is underdiagnosed and underreported in most of the continent; or the specific environmental conditions in French Guiana represent a unique niche for the disease to appear; or a sublineage of M. ulcerans has established in French Guiana that has a higher virulence than other members of the ancestral lineage found in the Americas.

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